Low Dose Naltrexone (LDN)
Prescription low-dose naltrexone designed to enhance immune function, reduce chronic inflammation, and support energy, pain relief, and long-term resilience.
Low Dose Naltrexone helps balance immune activity strengthening defense without driving chronic inflammation.
LDN helps restore daily energy, reduce inflammatory fatigue, and promote long-term vitality.
Supports healthy mood and stress regulation by naturally increasing the body's own endorphin levels.
Reclaim your natural vitality
To affect longevity, we must understand its pathways
Inflammation Reduction
LDN fine-tunes immune responses to counteract chronic "inflammaging," offering a pathway to healthier aging by reducing inflammation's negative effects on the body.
Endorphin Systems
LDN increases natural endorphin production, potentially affecting aging pathways tied to mood, pain perception, and overall well-being through the body's natural painkiller system.
Oxidative Stress
LDN reduces oxidative stress by enhancing the body's antioxidant defenses against harmful free radicals, slowing cellular wear and tear for more resilient aging.
Autoimmunity
LDN modulates chronic inflammatory responses by regulating cytokine release from immune cells, bringing inflammation closer to optimal levels and reducing tissue dysfunction.
Inflammation Reduction
LDN fine-tunes immune responses to counteract chronic "inflammaging," offering a pathway to healthier aging by reducing inflammation's negative effects on the body.
Endorphin Systems
LDN increases natural endorphin production, potentially affecting aging pathways tied to mood, pain perception, and overall well-being through the body's natural painkiller system.
Oxidative Stress
LDN reduces oxidative stress by enhancing the body's antioxidant defenses against harmful free radicals, slowing cellular wear and tear for more resilient aging.
Autoimmunity
LDN modulates chronic inflammatory responses by regulating cytokine release from immune cells, bringing inflammation closer to optimal levels and reducing tissue dysfunction.
Inflammation Reduction
LDN fine-tunes immune responses to counteract chronic "inflammaging," offering a pathway to healthier aging by reducing inflammation's negative effects on the body.
Endorphin Systems
LDN increases natural endorphin production, potentially affecting aging pathways tied to mood, pain perception, and overall well-being through the body's natural painkiller system.
Oxidative Stress
LDN reduces oxidative stress by enhancing the body's antioxidant defenses against harmful free radicals, slowing cellular wear and tear for more resilient aging.
Autoimmunity
LDN modulates chronic inflammatory responses by regulating cytokine release from immune cells, bringing inflammation closer to optimal levels and reducing tissue dysfunction.
Inflammation Reduction
LDN fine-tunes immune responses to counteract chronic "inflammaging," offering a pathway to healthier aging by reducing inflammation's negative effects on the body.
Endorphin Systems
LDN increases natural endorphin production, potentially affecting aging pathways tied to mood, pain perception, and overall well-being through the body's natural painkiller system.
Oxidative Stress
LDN reduces oxidative stress by enhancing the body's antioxidant defenses against harmful free radicals, slowing cellular wear and tear for more resilient aging.
Autoimmunity
LDN modulates chronic inflammatory responses by regulating cytokine release from immune cells, bringing inflammation closer to optimal levels and reducing tissue dysfunction.
Included with Low dose Naltrexone
When you sign up with us we work together to create a personalized protocol using the latest innovative medicine, practicing physicians, and flexible care based around real data and plan-included testing.
When you sign up with us we work together to create a personalized protocol using the latest innovative medicine, practicing physicians, and flexible care based around real data and plan-included testing.
Reviews
96 reviews
Healthspan is amazing!!!
Kristen was fantastic …she was kind, informative and professional. She helped me in my journey to Health and longevity! Thank you!!
Healthspan continues to be cutting edge
Healthspan continues to be cutting edge with regard to health and longevity. Brandon was knowledgeable and supportive. The details of the study were explained well and in detail.
Great experience with Healthspan
I’ve had a great experience with Healthspan. All of the representatives have been extremely responsive when sending messages on the portal, and I had a great call reviewing my initial labs with Brandon Fell who was extremely knowledgeable and courteous. I’ve started the Rapamycin and Acarbose protocol, and I’m looking forward to seeing what my updated labs will show in a couple months!
Frequently asked questions
LDN is a low-dose formulation of naltrexone used to enhance immune function, combat fatigue, and reduce chronic inflammation in autoimmune and pain-related conditions.
LDN temporarily blocks opioid receptors, prompting the body to increase its production of endorphins. It also inhibits TLR4 and reduces microglial inflammation—lowering chronic inflammation and oxidative stress.
LDN is used off-label to support fibromyalgia, long COVID, MS, Crohn’s disease, rheumatoid arthritis, and chronic fatigue-related conditions. Study →
Naltrexone is FDA-approved at higher doses for substance use disorders. LDN is prescribed off-label for reducing chronic inflammation, immune support, and chronic pain.
Some users report better sleep or mood within 1–2 weeks. Most experience significant results in energy, inflammation, and cognitive function by 6–8 weeks.
Yes. Many clients use LDN alongside Rapamycin, Methylene Blue, or Oxytocin for multi-pathway support.
LDN is generally well-tolerated. Mild side effects like vivid dreams, nausea, or temporary sleep disturbances may occur and usually resolve quickly.
Avoid concurrent use with opioids. Always consult your Healthspan clinician to check for drug interactions.
Starting doses range from 1mg–1.5mg, titrated to 4.5mg daily based on tolerance and response.
Most users benefit from 6–12 months of consistent use. Long-term use may help maintain results for chronic inflammation and fatigue.
LDN is a low-dose formulation of naltrexone used to enhance immune function, combat fatigue, and reduce chronic inflammation in autoimmune and pain-related conditions.
LDN temporarily blocks opioid receptors, prompting the body to increase its production of endorphins. It also inhibits TLR4 and reduces microglial inflammation—lowering chronic inflammation and oxidative stress.
LDN is used off-label to support fibromyalgia, long COVID, MS, Crohn’s disease, rheumatoid arthritis, and chronic fatigue-related conditions. Study →
Naltrexone is FDA-approved at higher doses for substance use disorders. LDN is prescribed off-label for reducing chronic inflammation, immune support, and chronic pain.
Some users report better sleep or mood within 1–2 weeks. Most experience significant results in energy, inflammation, and cognitive function by 6–8 weeks.
Yes. Many clients use LDN alongside Rapamycin, Methylene Blue, or Oxytocin for multi-pathway support.
LDN is generally well-tolerated. Mild side effects like vivid dreams, nausea, or temporary sleep disturbances may occur and usually resolve quickly.
Avoid concurrent use with opioids. Always consult your Healthspan clinician to check for drug interactions.
Starting doses range from 1mg–1.5mg, titrated to 4.5mg daily based on tolerance and response.
Most users benefit from 6–12 months of consistent use. Long-term use may help maintain results for chronic inflammation and fatigue.
