Autophagy Blend
Activate your body’s natural cellular cleanup system. The Autophagy Blend supports the breakdown of damaged proteins and organelles to improve mitochondrial function, lower inflammation, and enhance long-term metabolic resilience.
Helps your body clear out old, damaged parts of cells so they can work better and stay healthier.
Boosts how your cells make energy, so you feel more steady and less drained during the day.
Eases chronic inflammation and immune stress—key drivers of age-related decline.
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Unlock the science of metabolic activation
To affect longevity, we must understand its pathways
Autophagy & Cellular Cleanup
The Autophagy Blend contains quercetin phytosomes, spermidine, and L-ergothioneine to upregulate autophagy genes and pathways, activating the cell's recycling system to remove toxic aggregates and dysfunctional organelles.
mTOR Regulation
The blend modulates mTORC1 signaling to promote healthy balance between growth and repair phases, preventing excessive activation that speeds aging by prioritizing growth over necessary cellular maintenance.
NAD⁺ & Sirtuin Activation
Niacinamide supports NAD⁺ availability for sirtuin enzymes that maintain genomic stability, preserving efficient energy metabolism and facilitating DNA repair processes fundamental to healthy aging.
Mitochondrial Function
Antioxidant-rich ingredients reduce reactive oxygen species to protect mitochondrial membranes from oxidative damage, improving endurance, energy levels, and overall metabolic flexibility.
Inflammatory Pathway Control
Polyphenols and bioactive compounds moderate inflammatory pathways like NF-κB, reducing chronic "inflammaging" stress that erodes tissue function and accelerates cellular damage.
Insulin/IGF-1 Signaling
Autophagy-supporting ingredients help stabilize insulin sensitivity and glucose handling, creating a more balanced insulin/IGF-1 axis associated with healthier aging and metabolic resilience.
Fasting-Mimetic Mechanisms
Compounds like spermidine mimic caloric restriction benefits, enhancing autophagy and metabolic flexibility without requiring strict fasting regimens while efficiently mobilizing lipid stores.
Autophagy & Cellular Cleanup
The Autophagy Blend contains quercetin phytosomes, spermidine, and L-ergothioneine to upregulate autophagy genes and pathways, activating the cell's recycling system to remove toxic aggregates and dysfunctional organelles.
mTOR Regulation
The blend modulates mTORC1 signaling to promote healthy balance between growth and repair phases, preventing excessive activation that speeds aging by prioritizing growth over necessary cellular maintenance.
NAD⁺ & Sirtuin Activation
Niacinamide supports NAD⁺ availability for sirtuin enzymes that maintain genomic stability, preserving efficient energy metabolism and facilitating DNA repair processes fundamental to healthy aging.
Mitochondrial Function
Antioxidant-rich ingredients reduce reactive oxygen species to protect mitochondrial membranes from oxidative damage, improving endurance, energy levels, and overall metabolic flexibility.
Inflammatory Pathway Control
Polyphenols and bioactive compounds moderate inflammatory pathways like NF-κB, reducing chronic "inflammaging" stress that erodes tissue function and accelerates cellular damage.
Insulin/IGF-1 Signaling
Autophagy-supporting ingredients help stabilize insulin sensitivity and glucose handling, creating a more balanced insulin/IGF-1 axis associated with healthier aging and metabolic resilience.
Fasting-Mimetic Mechanisms
Compounds like spermidine mimic caloric restriction benefits, enhancing autophagy and metabolic flexibility without requiring strict fasting regimens while efficiently mobilizing lipid stores.
Autophagy & Cellular Cleanup
The Autophagy Blend contains quercetin phytosomes, spermidine, and L-ergothioneine to upregulate autophagy genes and pathways, activating the cell's recycling system to remove toxic aggregates and dysfunctional organelles.
mTOR Regulation
The blend modulates mTORC1 signaling to promote healthy balance between growth and repair phases, preventing excessive activation that speeds aging by prioritizing growth over necessary cellular maintenance.
NAD⁺ & Sirtuin Activation
Niacinamide supports NAD⁺ availability for sirtuin enzymes that maintain genomic stability, preserving efficient energy metabolism and facilitating DNA repair processes fundamental to healthy aging.
Mitochondrial Function
Antioxidant-rich ingredients reduce reactive oxygen species to protect mitochondrial membranes from oxidative damage, improving endurance, energy levels, and overall metabolic flexibility.
Inflammatory Pathway Control
Polyphenols and bioactive compounds moderate inflammatory pathways like NF-κB, reducing chronic "inflammaging" stress that erodes tissue function and accelerates cellular damage.
Insulin/IGF-1 Signaling
Autophagy-supporting ingredients help stabilize insulin sensitivity and glucose handling, creating a more balanced insulin/IGF-1 axis associated with healthier aging and metabolic resilience.
Fasting-Mimetic Mechanisms
Compounds like spermidine mimic caloric restriction benefits, enhancing autophagy and metabolic flexibility without requiring strict fasting regimens while efficiently mobilizing lipid stores.
Autophagy & Cellular Cleanup
The Autophagy Blend contains quercetin phytosomes, spermidine, and L-ergothioneine to upregulate autophagy genes and pathways, activating the cell's recycling system to remove toxic aggregates and dysfunctional organelles.
mTOR Regulation
The blend modulates mTORC1 signaling to promote healthy balance between growth and repair phases, preventing excessive activation that speeds aging by prioritizing growth over necessary cellular maintenance.
NAD⁺ & Sirtuin Activation
Niacinamide supports NAD⁺ availability for sirtuin enzymes that maintain genomic stability, preserving efficient energy metabolism and facilitating DNA repair processes fundamental to healthy aging.
Mitochondrial Function
Antioxidant-rich ingredients reduce reactive oxygen species to protect mitochondrial membranes from oxidative damage, improving endurance, energy levels, and overall metabolic flexibility.
Inflammatory Pathway Control
Polyphenols and bioactive compounds moderate inflammatory pathways like NF-κB, reducing chronic "inflammaging" stress that erodes tissue function and accelerates cellular damage.
Insulin/IGF-1 Signaling
Autophagy-supporting ingredients help stabilize insulin sensitivity and glucose handling, creating a more balanced insulin/IGF-1 axis associated with healthier aging and metabolic resilience.
Fasting-Mimetic Mechanisms
Compounds like spermidine mimic caloric restriction benefits, enhancing autophagy and metabolic flexibility without requiring strict fasting regimens while efficiently mobilizing lipid stores.
A naturally occurring compound produced by gut bacteria from the metabolism of ellagic acid and ellagitannins, found in foods like pomegranates and berries. Studies indicate Urolitin A has the potential to improve mitochondrial health, muscle strength, and other anti-aging effects.
Included with Autophagy Blend
When you sign up with us we work together to create a personalized protocol using the latest innovative medicine, practicing physicians, and flexible care based around real data and plan-included testing.
When you sign up with us we work together to create a personalized protocol using the latest innovative medicine, practicing physicians, and flexible care based around real data and plan-included testing.
Frequently asked questions
A specialized supplement that helps your body recycle damaged cellular components. It works best when cycled with the AMPK Blend in our Cellular Renewal Protocol.
Many notice shifts in energy or recovery in a few weeks. Deeper changes in markers like glucose or lipids may take 1–3 months.
Made in the U.S. at an FDA-registered, cGMP-certified facility.
Yes. All products are tested by a third party, and our facility is HACCP and cGMP certified.
Not required—but a whole-foods diet and moderate exercise can enhance the benefits. Some users add fasting for extra support.
If using alone, take 1–2 capsules once or twice daily. If cycling, use during the autophagy phase, then switch to AMPK. Take with food if sensitive.
No problem. Resume when you can. Short breaks won’t impact long-term results.
Not mandatory—but tracking things like glucose, insulin, or CRP can offer helpful feedback on how your body is responding.
A specialized supplement that helps your body recycle damaged cellular components. It works best when cycled with the AMPK Blend in our Cellular Renewal Protocol.
Many notice shifts in energy or recovery in a few weeks. Deeper changes in markers like glucose or lipids may take 1–3 months.
Made in the U.S. at an FDA-registered, cGMP-certified facility.
Yes. All products are tested by a third party, and our facility is HACCP and cGMP certified.
Not required—but a whole-foods diet and moderate exercise can enhance the benefits. Some users add fasting for extra support.
If using alone, take 1–2 capsules once or twice daily. If cycling, use during the autophagy phase, then switch to AMPK. Take with food if sensitive.
No problem. Resume when you can. Short breaks won’t impact long-term results.
Not mandatory—but tracking things like glucose, insulin, or CRP can offer helpful feedback on how your body is responding.
Reviews
96 reviews
Healthspan is amazing!!!
Kristen was fantastic …she was kind, informative and professional. She helped me in my journey to Health and longevity! Thank you!!
Healthspan continues to be cutting edge
Healthspan continues to be cutting edge with regard to health and longevity. Brandon was knowledgeable and supportive. The details of the study were explained well and in detail.
Great experience with Healthspan
I’ve had a great experience with Healthspan. All of the representatives have been extremely responsive when sending messages on the portal, and I had a great call reviewing my initial labs with Brandon Fell who was extremely knowledgeable and courteous. I’ve started the Rapamycin and Acarbose protocol, and I’m looking forward to seeing what my updated labs will show in a couple months!