In a recent episode of the Wise Athletes Podcast, Healthspan's founder and CEO, Daniel, shared his story. He talked about how his research on mTOR-driven aging and his wife's lymphoma relapse led him to create Healthspan. Daniel also explained the scientific research that informs the rapamycin protocol offered by Healthspan.In the podcast, he discusses:
- His background in studying mTOR inhibitors as potential interventions for neurodegenerative diseases.
- How his wife's lymphoma relapse pushed him to start a telemedicine clinic focused on mTOR dysfunction, cellular senescence, and metabolic dysfunction.
- The three fates of a damaged cells and how damaged senescent cells compound tissue decline over time.
- Dr. Mikhail Blagosklonny's foundational theory of cellular hyperfunctions and its implications for mTOR-driven aging and the usage of rapamycin.
- Exploring the relationship between mTOR overactivity and anabolic resistance, and examining the potential benefits of using rapamycin to restore sensitivity to muscle growth stimuli.
- The safety profile of rapamycin—what the Mannick study tells us about rapamycin and immune function and what the blood test of Healthspan's patients on the rapamycin protocol reveals.
- The limitations of anti-aging drugs and the importance of lifestyle interventions to increase healthspan.
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